SCHEMBL31044993

SCHEMBL31044993

CC(=O)c1nc(Cl)c2cc(C)sc2n1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 2/20 0.35
CSNK2B P67870 2/20 0.35
CSNK2A1 P68400 2/20 0.35
NOTUM Q6P988 1/20 0.35
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
MAPK1 P28482 1/20 0.35
KDM4E B2RXH2 3/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
POLB P06746 1/20 0.34
KMT2A Q03164 2/20 0.34
SLC14A1 Q13336 1/20 0.34
PLK1 P53350 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29991602 0.87 POLB (0.42) CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1
SCHEMBL31045214 0.84 KDM4E (0.38) CSNK2A2CSNK2BCSNK2A1ALDH1A1SMN1; SMN2
SCHEMBL163783 0.82 MAPT (0.40) CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1
SCHEMBL167507 0.79 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2KDM4EHTTKMT2A
SCHEMBL5432011 0.77 MAPT (0.37) CSNK2A2CSNK2BCSNK2A1ALDH1A1SMN1; SMN2
SCHEMBL1969445 0.77 KDM4E (0.36) CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1
SCHEMBL26038536 0.75 HTR2C (0.43) ALDH1A1SMN1; SMN2MAPK1KDM4EHTT
SCHEMBL7100819 0.73 CSNK2A2 (0.46) CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1
SCHEMBL29991488 0.72 KDM4E (0.34) ALDH1A1KDM4EMAPT
SCHEMBL8334672 0.72 RARA (0.41) ALDH1A1SMN1; SMN2KDM4EHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240279236-A1 COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS FIMBRION THERAPEUTICS, INC. (US) 2024-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240279236-A1 COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS G6PD, SDHA, NQO1 CSNK2A2 2712/4885CSNK2B 2783/4885CSNK2A1 2965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.