Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047361 | 0.80 | HCAR2 (0.41) | TSHRFSHRCKS1BSKP1SKP2 | |
| SCHEMBL31047360 | 0.80 | HCAR2 (0.41) | TSHRFSHRCKS1BSKP1SKP2 | |
| SCHEMBL31047337 | 0.80 | HCAR2 (0.41) | TSHRFSHRCKS1BSKP1SKP2 | |
| SCHEMBL31047324 | 0.72 | KIF18A (0.48) | — | |
| SCHEMBL31047332 | 0.70 | ACACB (0.38) | ACACBGAATSHRDYRK1A | |
| SCHEMBL116767 | 0.69 | MEN1 (0.65) | MEN1KMT2AMETAP1CYP3A4 | |
| SCHEMBL31047340 | 0.69 | IDH1 (0.37) | ACACBKCNQ3KCNQ2KMT2ATSHR | |
| SCHEMBL31047342 | 0.69 | IDH1 (0.37) | ACACBKCNQ3KCNQ2KMT2ATSHR | |
| SCHEMBL2396852 | 0.67 | ALDH1A1 (0.63) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL17336621 | 0.66 | TRPV1 (0.46) | BRD9GSK3BDYRK1ARXFP1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149189-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-18 | — | — | WO | disclosed |