Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 8/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047343 | 0.85 | OPRM1 (0.43) | OPRM1OPRD1OGFRL1GFEREGFR | |
| SCHEMBL30842139 | 0.78 | TGFBR1 (0.49) | OPRM1OPRD1OGFRL1GFERRXFP1 | |
| SCHEMBL31047350 | 0.71 | TSHR (0.37) | OPRM1OPRD1OGFRL1RXFP1BRD4 | |
| SCHEMBL31047351 | 0.71 | TSHR (0.37) | OPRM1OPRD1OGFRL1RXFP1BRD4 | |
| SCHEMBL3825019 | 0.69 | TLR7 (0.42) | BRD4P2RX7 | |
| SCHEMBL30842143 | 0.69 | OPRM1 (0.40) | OPRM1OPRD1OGFRL1RXFP1OPRK1 | |
| SCHEMBL31613842 | 0.68 | OPRM1 (0.39) | OPRM1OPRD1OGFRL1RXFP1BRD4 | |
| SCHEMBL31613833 | 0.68 | RXFP1 (0.36) | OPRM1OPRD1OGFRL1RXFP1BRD4 | |
| SCHEMBL31613824 | 0.68 | POLB (0.40) | OPRM1OPRD1OGFRL1BRD4METAP1 | |
| SCHEMBL30842140 | 0.67 | POLB (0.42) | OPRM1OPRD1OGFRL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149189-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-18 | — | — | WO | disclosed |