Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220634 | 0.84 | CYP2C19 (0.54) | ALDH1A1HPGDKDM4EGAACYP1A2 | |
| SCHEMBL4943635 | 0.84 | GAA (0.59) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL2880191 | 0.84 | LMNA (0.54) | ALDH1A1HPGDGAARAB9ANPC1 | |
| SCHEMBL31680675 | 0.84 | TRPV1 (0.64) | KDM4ERAB9AMAPTKMT2AMEN1 | |
| SCHEMBL6101638 | 0.84 | NQO2 (0.51) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL487254 | 0.84 | TRPV1 (0.64) | KDM4ERAB9AMAPTKMT2AMEN1 | |
| SCHEMBL29481043 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL4805597 | 0.83 | RXFP1 (0.45) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL5622577 | 0.83 | MEN1 (0.45) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL283066 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDKDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311813-B | Palladium-catalyzed meta-C-H functionalized universal ligands | 斯克利普斯研究院 | 2023-02-28 | — | — | CN | disclosed |
| CN-107001274-A | It is used as 4 (base of 4 (base of 4 phenyl urea groups naphthalene 1) epoxide pyridine 2) aminobenzoic acid derivatives of P38 kinase inhibitors | 瑞斯比维特有限公司 | 2017-08-01 | — | — | CN | disclosed |
| WO-2017106426-A1 | FE NANOPARTICLES WITH PPM CONTENTS OF PD, CU AND/OR NI, REACTIONS IN WATER CATALYZED BY THEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-22 | — | — | WO | disclosed |
| US-20170173569-A1 | Fe-ppm Pd, Cu and/or Ni Nanoparticle-Catalyzed Reactions in Water | LIPSHUTZ BRUCE H (US) | 2017-06-22 | — | — | US | disclosed |
| US-20170173569-A1 | Fe-ppm Pd, Cu and/or Ni Nanoparticle-Catalyzed Reactions in Water | LIPSHUTZ BRUCE H (US) | 2017-06-22 | — | — | US | disclosed |
| CN-106573914-A | Pyrazolyl-ureas as kinase inhibitors | 瑞斯比维特有限公司 | 2017-04-19 | — | — | CN | disclosed |
| US-9346795-B2 | Substituted sulfonamides useful as antiapoptotic Bcl inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| US-8017640-B2 | Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment | UNIVERSITY OF BRADFORD (GB) | 2011-09-13 | — | — | US | disclosed |
| US-20070161669-A1 | Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment | SCHOOL OF PHARMACY UNIVERSITY OF LONDON | 2007-07-12 | — | — | US | disclosed |
| US-6608052-B2 | An mono or polycyclic aromatic or heteroaromatic carbamate or urea or thiacarbamoyl derivatives; inhibit production of cytokines involved in inflammatory processes | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-08-19 | — | — | US | disclosed |
| US-20030092702-A1 | Novel carbamate and oxamide compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | US | disclosed |
| WO-2002096876-A1 | CARBAMATE AND OXAMIDE COMPOUNDS AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002083642-A1 | COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| US-20020082256-A1 | Compounds useful as anti-inflammatory agents | BETAGERI RAJASHEHAR (US) | 2002-06-27 | — | — | US | disclosed |
| US-20020055507-A1 | Compounds useful as anti-inflammatory agents | BETAGERI RAJASHEHAR (US) | 2002-05-09 | — | — | US | disclosed |
| US-6358945-B1 | CYTOKINE, TUMOR NECROSIS FACTOR, AND INTERLEUKIN INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | disclosed |
| US-20020032195-A1 | Compounds useful as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-14 | — | — | US | disclosed |
| EP-1165516-A2 | HETEROCYCLIC UREA AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000055139-A2 | HETEROCYCLIC UREA AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032195-A1 | Compounds useful as anti-inflammatory agents | MPO, EPX, PTGES | ALDH1A1 391/4885HPGD 117/4885KDM4E 2498/4885 |
| US-20030092702-A1 | Novel carbamate and oxamide compounds | IFNG, CXCR1, ARG1 | ALDH1A1 1014/4885HPGD 354/4885KDM4E 92/4885 |
| US-20170173569-A1 | Fe-ppm Pd, Cu and/or Ni Nanoparticle-Catalyzed Reactions in Water | TPR, SOD1, ZNF207 | ALDH1A1 1764/4885HPGD 1002/4885KDM4E 1803/4885 |
| US-20020082256-A1 | Compounds useful as anti-inflammatory agents | NFKBIA, TNF, MPO | ALDH1A1 388/4885HPGD 132/4885KDM4E 3302/4885 |
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BCL2, BAX, BCL2A1 | ALDH1A1 2963/4885HPGD 1804/4885KDM4E 2440/4885 |
| US-20070161669-A1 | Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment | CYP1B1, CYP1A1, RECQL | ALDH1A1 216/4885HPGD 229/4885KDM4E 1039/4885 |
| US-20020055507-A1 | Compounds useful as anti-inflammatory agents | NFKBIA, TNF, MPO | ALDH1A1 388/4885HPGD 132/4885KDM4E 3302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.