SCHEMBL3104816

SCHEMBL3104816

C=CC(=O)Oc1cc(C)ccc1-c1ccc(C=CC(=O)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
CYP3A4 P08684 3/20 0.55
ALDH1A1 P00352 1/20 0.55
HPGD P15428 1/20 0.55
CYP1B1 Q16678 2/20 0.49
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
BCHE P06276 2/20 0.46
NFKB1 P19838 2/20 0.46
NFKB2 Q00653 2/20 0.46
RELA Q04206 2/20 0.46
MAOB P27338 2/20 0.45
PLIN1 O60240 1/20 0.45
TNFRSF1A P19438 1/20 0.45
ACHE P22303 1/20 0.45
RECQL P46063 1/20 0.45
PLIN5 Q00G26 1/20 0.45
ABHD5 Q8WTS1 1/20 0.45
RAB9A P51151 2/20 0.44
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27596144 0.82 MAPT (0.53) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL29220679 0.81 LMNA (0.37) ALDH1A1HPGDLMNAL3MBTL1
SCHEMBL27591346 0.79 NFE2L2 (0.61) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL7543053 0.77 CYP3A4 (0.66) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL7543059 0.77 CYP3A4 (0.66) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL19804022 0.76 THRB (0.42) LMNAL3MBTL1
SCHEMBL27977352 0.75 MAPT (0.90) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL8964978 0.75 MAOB (0.69) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL8964970 0.75 MAOB (0.69) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL23789072 0.74 MAPT (0.87) MAPTCYP3A4ALDH1A1HPGDCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7787085-B2 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2010-08-31 US disclosed
US-20080123046-A1 OPTICAL ALIGNMENT METHOD AND LIQUID CRYSTAL DISPLAY ELEMENT JSR CORPORATION (JP) 2008-05-29 US disclosed
US-20050259203-A1 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2005-11-24 US disclosed
EP-1353217-A1 Optical alignment method and liquid crystal display element JSR Corporation (JP) 2003-10-15 EP disclosed