Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 5/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049269 | 0.89 | ALDH1A1 (0.35) | ALDH1A1HPGDPLAUELANEGAA | |
| SCHEMBL31049371 | 0.87 | ALDH1A1 (0.34) | ALDH1A1HPGDHDAC1HDAC6PLAU | |
| SCHEMBL31049388 | 0.84 | MEN1 (0.33) | ALDH1A1HPGDJAK2HDAC1HDAC6 | |
| SCHEMBL31049273 | 0.81 | REN (0.33) | ALDH1A1HPGDJAK2JAK3 | |
| SCHEMBL31049571 | 0.73 | ALDH1A1 (0.36) | ALDH1A1HPGDPLAUELANEGAA | |
| SCHEMBL31049408 | 0.72 | IP6K1 (0.32) | — | |
| SCHEMBL31049362 | 0.67 | — | — | |
| SCHEMBL31049393 | 0.66 | ICMT (0.41) | ALDH1A1HPGDPLAUELANEGAA | |
| SCHEMBL31049268 | 0.64 | ALDH1A1 (0.36) | ALDH1A1HPGDPLAUELANEGAA | |
| SCHEMBL31049315 | 0.62 | ALDH1A1 (0.42) | ALDH1A1HPGDPLAUELANEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |