Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12508320 | 0.82 | AKR1C3 (0.58) | ENPP2AKR1C3AKR1C2ATMLMNA | |
| SCHEMBL8675 | 0.80 | ENPP2 (1.00) | ENPP2CA1CA2PTGS2 | |
| SCHEMBL6096 | 0.79 | ENPP2 (0.61) | ENPP2SMN1; SMN2GAA | |
| SCHEMBL25281522 | 0.77 | BRPF1 (0.48) | ENPP2CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL23247995 | 0.77 | ENPP2 (0.50) | ENPP2AKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL205203 | 0.77 | CA2 (0.80) | ENPP2CA1CA2 | |
| SCHEMBL31354846 | 0.77 | CA2 (0.80) | ENPP2CA1CA2 | |
| SCHEMBL13203351 | 0.75 | AKR1C3 (0.52) | ENPP2AKR1C3AKR1C2ATMLMNA | |
| SCHEMBL16968554 | 0.75 | ENPP2 (0.88) | ENPP2CA1CA2PTGS2 | |
| SCHEMBL8035317 | 0.75 | ENPP2 (0.61) | ENPP2AKR1C3AKR1C2ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715015-A | Selective PHD1 inhibitor compounds, compositions and methods of use | 阿克比治疗有限公司 | 2024-09-27 | — | — | CN | disclosed |