Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LGMN | Q99538 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PRKDC | P78527 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21807926 | 1.00 | LMNA (0.46) | LMNALGMNCDK1CDK2PIK3CA | |
| SCHEMBL15918731 | 0.83 | CHKA (0.52) | LMNAMAPTMEN1ALDH1A1HTT | |
| SCHEMBL29529691 | 0.81 | HRH4 (0.54) | LMNAMAPTNPC1RAB9AMEN1 | |
| SCHEMBL27936855 | 0.80 | LRRK2 (0.59) | LMNALGMNCDK1CDK2PIK3CA | |
| SCHEMBL31051504 | 0.79 | HRH4 (0.59) | MAPTNPC1RAB9AMEN1HTT | |
| SCHEMBL21807915 | 0.79 | HRH4 (0.59) | MAPTNPC1RAB9AMEN1HTT | |
| SCHEMBL3304237 | 0.79 | LMNA (0.46) | LMNALGMNCDK1CDK2PIK3CA | |
| SCHEMBL3724026 | 0.79 | LMNA (0.46) | LMNALGMNCDK1CDK2PIK3CA | |
| SCHEMBL30900618 | 0.79 | LMNA (0.46) | LMNALGMNCDK1CDK2PIK3CA | |
| SCHEMBL17706687 | 0.79 | LGMN (0.49) | LMNALGMNCDK1CDK2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166137-B | O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside enzyme inhibitors | 比奥根MA公司 | 2024-08-16 | — | — | CN | disclosed |