Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.54 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.52 |
| ▸ | CHKA | P35790 | 2/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | S100B | P04271 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15918731 | 0.98 | CHKA (0.52) | HRH4ELOVL1CHKATERTMAPT | |
| SCHEMBL21807915 | 0.81 | HRH4 (0.59) | HRH4MAPTMEN1GAAHTT | |
| SCHEMBL31051504 | 0.81 | HRH4 (0.59) | HRH4MAPTMEN1GAAHTT | |
| SCHEMBL27102997 | 0.81 | ADRB2 (0.56) | HRH4MAPTALDH1A1HTTTP53 | |
| SCHEMBL21807926 | 0.81 | LMNA (0.46) | MAPTMEN1ALDH1A1ALOX15HTT | |
| SCHEMBL31051506 | 0.81 | LMNA (0.46) | MAPTMEN1ALDH1A1ALOX15HTT | |
| Hydrochloric Acid SCHEMBL23302654 | 0.80 | ADRB2 (0.55) | HRH4MAPTALDH1A1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL29882400 | 0.80 | ADRB2 (0.55) | HRH4MAPTALDH1A1HTTKDM4E | |
| SCHEMBL5847761 | 0.77 | HRH4 (0.54) | HRH4ELOVL1CHKATERTMAPT | |
| SCHEMBL6262576 | 0.77 | HRH4 (0.54) | HRH4ELOVL1CHKATERTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250275952-A1 | 4-METHYLSULFONYL-SUBSTITUTED PIPERIDINE UREA COMPOUNDS | MYOKARDIA INC (US) | 2025-09-04 | — | — | US | disclosed |
| US-20220117955-A1 | 4-METHYLSULFONYL-SUBSTITUTED PIPERIDINE UREA COMPOUNDS | MyoKardia, Inc. | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250275952-A1 | 4-METHYLSULFONYL-SUBSTITUTED PIPERIDINE UREA COMPOUNDS | TNNI3, UMPS, TNNT2 | HRH4 1185/4885ELOVL1 3705/4885CHKA 2417/4885 |
| US-20220117955-A1 | 4-METHYLSULFONYL-SUBSTITUTED PIPERIDINE UREA COMPOUNDS | TNNI3, UMPS, TNNT2 | HRH4 1185/4885ELOVL1 3705/4885CHKA 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.