Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052685 | 0.75 | KDM4E (0.39) | GRK6ALDH1A1IRAK1IRAK4HPGD | |
| SCHEMBL2791668 | 0.72 | PKM (0.62) | PKMPOLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5726227 | 0.69 | MAPT (0.62) | POLBGRK6ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2062401 | 0.69 | ALDH1A1 (0.35) | LCKALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL7295476 | 0.68 | ALDH1A1 (0.50) | PKMPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3294386 | 0.67 | TSHR (0.46) | ALDH1A1HPGDLMNASMN1; SMN2MAPT | |
| SCHEMBL18109861 | 0.65 | BACE1 (0.41) | GRK6ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3492762 | 0.63 | MEN1 (0.55) | POLBALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL10025753 | 0.63 | PAX8 (0.39) | ALDH1A1IRAK4LMNASMN1; SMN2MAPT | |
| SCHEMBL11781231 | 0.63 | MMP14 (0.62) | POLBALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676923-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | Cancer Research Technology Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184550-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |