Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29736634 | 0.80 | HRH3 (0.59) | HRH3NOS2NOS1NOS3 | |
| SCHEMBL23104383 | 0.80 | HRH3 (0.59) | HRH3NOS2NOS1NOS3 | |
| SCHEMBL31052452 | 0.75 | PKM (0.35) | KDM4ERXFP1IRAK1IRAK4ALDH1A1 | |
| SCHEMBL10490484 | 0.74 | HRH3 (0.42) | KDM4EHRH3NOS2NOS1NOS3 | |
| SCHEMBL7295476 | 0.73 | ALDH1A1 (0.50) | KDM4EALDH1A1KMT2ALMNATSHR | |
| SCHEMBL2791734 | 0.71 | HCAR3 (0.38) | KDM4ERXFP1HRH3IRAK1IRAK4 | |
| SCHEMBL29907766 | 0.70 | NOS3 (0.50) | KDM4ENOS2NOS1NOS3ALDH1A1 | |
| SCHEMBL1097604 | 0.70 | NOS3 (0.50) | KDM4ENOS2NOS1NOS3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3335648 | 0.69 | NOS3 (0.48) | KDM4ENOS2NOS1NOS3ALDH1A1 | |
| SCHEMBL14511097 | 0.68 | ALDH1A1 (0.36) | KDM4ERXFP1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676923-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | Cancer Research Technology Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184550-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |