Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105338 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9251495 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9251499 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11813693 | 0.82 | L3MBTL1 (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11813691 | 0.82 | L3MBTL1 (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11812725 | 0.78 | CA1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11812719 | 0.78 | CA1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22319906 | 0.78 | ABHD6 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3114278 | 0.75 | LMNA (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3114283 | 0.75 | LMNA (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200385340-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | BIOTRON LTD (AU) | 2020-12-10 | — | — | US | disclosed |
| US-10683263-B2 | Antiviral compounds and methods | BIOTRON LIMITED (AU) | 2020-06-16 | — | — | US | disclosed |
| EP-2826770-B1 | ACYLGUANIDINE COMPOUNDS WITH ANTIVIRAL ACTIVITY | BIOTRON LTD (AU) | 2018-09-12 | — | — | EP | disclosed |
| US-20170362170-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | BIOTRON LTD (AU) | 2017-12-21 | — | — | US | disclosed |
| US-20160376231-A1 | ANTIVIRAL COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2016-12-29 | — | — | US | disclosed |
| EP-2659885-B1 | Hepatitis C Antiviral Compositions and Methods | BIOTRON LTD (AU) | 2016-11-09 | — | — | EP | disclosed |
| US-9440926-B2 | Antiviral compounds and methods | BIOTRON LIMITED (AU) | 2016-09-13 | — | — | US | disclosed |
| EP-2194976-B1 | Hepatitis C antiviral compositions comprising 5-(1-methylpyrazol-4-yl)2-naphthoylguanidine and 2'-C-methyladenosine or 2'-C-methylcytidine | BIOTRON LTD (AU) | 2015-12-09 | — | — | EP | disclosed |
| US-20150023921-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | BIOTRON LIMITED (AU) | 2015-01-22 | — | — | US | disclosed |
| EP-2826770-A1 | Acylguanidine compounds with antiviral activity | Biotron Limited (AU) | 2015-01-21 | — | — | EP | disclosed |
| CN-103274970-A | Antiviral compounds and methods | BIOTRON LTD | 2013-09-04 | — | — | CN | disclosed |
| CN-101208297-B | Antiviral compounds and methods | BIOTRON LTD | 2013-04-24 | — | — | CN | disclosed |
| US-20100254942-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | BIOTRON LIMITED (AU) | 2010-10-07 | — | — | US | disclosed |
| CN-101827589-A | Hepatitis c antiviral compositions and methods | BIOTROM LTD | 2010-09-08 | — | — | CN | disclosed |
| EP-2194976-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | Biotron Limited (AU) | 2010-06-16 | — | — | EP | disclosed |
| US-20090099239-A1 | Antiviral Compounds and Methods | BIOTRON LIMITED (AU) | 2009-04-16 | — | — | US | disclosed |
| WO-2009018609-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | BIOTROM LIMITED (AU) | 2009-02-12 | — | — | WO | disclosed |
| CN-101208297-A | Antiviral compounds and methods | BIOTRON LTD (AU) | 2008-06-25 | — | — | CN | disclosed |
| EP-1902017-A1 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2008-03-26 | — | — | EP | disclosed |
| WO-2006135978-A1 | ANTIVIRAL COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100254942-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | HAVCR2, HCCS, EIF2AK2 | ALDH1A1 2228/4885MAPT 4416/4885KDM4E 3855/4885 |
| US-20150023921-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | HAVCR2, HCCS, EIF2AK2 | ALDH1A1 2228/4885MAPT 4416/4885KDM4E 3855/4885 |
| US-10683263-B2 | Antiviral compounds and methods | MAVS, ZC3HAV1, EIF2AK2 | ALDH1A1 3086/4885MAPT 4471/4885KDM4E 2925/4885 |
| US-20170362170-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | HAVCR2, HCCS, EIF2AK2 | ALDH1A1 2228/4885MAPT 4416/4885KDM4E 3855/4885 |
| US-20090099239-A1 | Antiviral Compounds and Methods | MAVS, ZC3HAV1, EIF2AK2 | ALDH1A1 3086/4885MAPT 4471/4885KDM4E 2925/4885 |
| US-20160376231-A1 | ANTIVIRAL COMPOUNDS AND METHODS | MAVS, ZC3HAV1, EIF2AK2 | ALDH1A1 3086/4885MAPT 4471/4885KDM4E 2925/4885 |
| US-20200385340-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | HAVCR2, HCCS, EIF2AK2 | ALDH1A1 2228/4885MAPT 4416/4885KDM4E 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.