Sugi Predict

Sugi Predict / Compounds / SCHEMBL3105430

SCHEMBL3105430

SCHEMBL3105430

CON(Cl)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA4 P22748 2/20 0.38
▸ KMT2A Q03164 4/20 0.37
▸ HTT P42858 2/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ CA12 O43570 2/20 0.37
▸ CA1 P00915 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ CA9 Q16790 2/20 0.37
▸ ALDH1A1 P00352 6/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ CA7 P43166 1/20 0.33
▸ CA14 Q9ULX7 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TSHR P16473 3/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10358899 0.73 ALDH1A1 (0.38) KMT2AHTTMEN1CA12CA1
SCHEMBL3951063 0.72 CA4 (0.41) CA4KMT2AHTTMEN1CA12
SCHEMBL210129 0.72 CA4 (0.41) CA4KMT2AHTTMEN1CA12
SCHEMBL9417468 0.72 LTA4H (0.39) CA4KMT2AHTTMEN1CA12
Hydrochloric Acid SCHEMBL21273293 0.70 CA4 (0.39) CA4KMT2AHTTMEN1CA12
SCHEMBL2742440 0.70 MEN1 (0.44) CA4KMT2AHTTMEN1CA12
Hydrochloric Acid SCHEMBL9721484 0.70 CA4 (0.39) CA4KMT2AHTTMEN1CA12
SCHEMBL3108688 0.69 — —
Methoxymethane SCHEMBL28621428 0.69 ALDH1A1 (0.55) CA4KMT2AHTTMEN1CA12
SCHEMBL3964832 0.68 CA4 (0.38) CA4KMT2AHTTMEN1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234343-A1 INHIBITORS OF ION CHANNELS ICAGEN, INC. (US) 2010-09-16 — — US claimed
US-7705158-B2 Inhibitors of ion channels ICAGEN, INC. (US) 2010-04-27 — — US claimed
US-8338608-B2 Inhibitors of ion channels ICAGEN INC. (US) 2012-12-25 — — US disclosed
US-20100234343-A1 INHIBITORS OF ION CHANNELS ICAGEN, INC. (US) 2010-09-16 — — US disclosed
US-7705158-B2 Inhibitors of ion channels ICAGEN, INC. (US) 2010-04-27 — — US disclosed
EP-1945029-A2 INHIBITORS OF ION CHANNELS Icagen, Inc. (US) 2008-07-23 — — EP disclosed
US-20070135493-A1 INHIBITORS OF ION CHANNELS ICAGEN (US) 2007-06-14 — — US disclosed
WO-2007056099-A2 INHIBITORS OF ION CHANNELS ICAGEN, INC. (US) 2007-05-18 — — WO disclosed
CN-1946811-A High-purity naphthol as pigments CLARIANT GMBH (DE) 2007-04-11 — — CN disclosed
US-3965087-A Trisazo dye containing a diphenylenesulfone structure SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) 1976-06-22 — — US disclosed
US-3951941-A POLYAZODYE SAKAI CHEMICAL INDUSTRY COMPANY, LIMITED (JA) 1976-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234343-A1 INHIBITORS OF ION CHANNELS TRPV1, TRPV5, TRPA1 CA4 1080/4885KMT2A 1920/4885HTT 862/4885
US-20070135493-A1 INHIBITORS OF ION CHANNELS TRPV1, TRPV5, TRPA1 CA4 1080/4885KMT2A 1920/4885HTT 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.