Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31180919 | 0.80 | MEN1 (0.51) | NPSR1GPR55MEN1KMT2AUSP2 | |
| SCHEMBL7336651 | 0.79 | MEN1 (0.50) | NPSR1GPR55MEN1KMT2AUSP2 | |
| SCHEMBL746788 | 0.70 | ADRB1 (0.47) | NPSR1GPR55MEN1KMT2AUSP2 | |
| SCHEMBL12339300 | 0.70 | SOS1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6830556 | 0.69 | ADRB1 (0.46) | NPSR1GPR55MEN1KMT2AUSP2 | |
| SCHEMBL219432 | 0.69 | MEN1 (1.00) | MEN1KMT2AUSP2CYP2D6CYP2C9 | |
| SCHEMBL2794662 | 0.69 | MEN1 (1.00) | MEN1KMT2AUSP2CYP2D6CYP2C9 | |
| SCHEMBL26094127 | 0.68 | MEN1 (0.62) | NPSR1GPR55MEN1KMT2AUSP2 | |
| SCHEMBL3712349 | 0.68 | SIGMAR1 (0.54) | MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL23033502 | 0.68 | NPSR1 (0.39) | NPSR1GPR55MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451952-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof | 标新生物医药科技(上海)有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-118556047-A | Oxo-isoindolinyl substituted piperidinedione derivative and application thereof | 标新生物医药科技(上海)有限公司 | 2024-08-27 | — | — | CN | disclosed |