Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6830556 | 0.98 | ADRB1 (0.46) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL27419645 | 0.86 | ADRB1 (0.44) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL7647236 | 0.84 | ADRB1 (0.52) | ADRB1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL4487460 | 0.82 | ADRB1 (0.50) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL38662505 | 0.82 | ADRB2 (0.50) | HTR2AHTR2CHTR2BUSP2CYP2D6 | |
| SCHEMBL7940843 | 0.82 | HTR2B (0.36) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL8797791 | 0.82 | ADRB1 (0.44) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL7943366 | 0.82 | MAPT (0.38) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL6374876 | 0.81 | ADRB1 (0.49) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL23777713 | 0.80 | HTR3E (0.55) | ADRB1SIGMAR1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557411-B1 | N-PHENYL-(2R,5S)DIMETHYLPIPERAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2012-10-17 | — | — | EP | claimed |
| CN-114404588-A | Compounds and methods for inhibiting phosphate transport | 阿德利克斯公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-105979959-B | Compounds and methods for inhibiting phosphate transport | 阿德利克斯公司 | 2021-11-30 | — | — | CN | disclosed |
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2020-07-02 | — | — | US | disclosed |
| CN-111093648-A | Compositions and methods for treating myopia | 艾伦实验室股份有限公司 | 2020-05-01 | — | — | CN | disclosed |
| EP-3363645-B1 | PRETREATMENT OF UV CURED INK UNDER-LAYERS | XEROX CORP (US) | 2019-10-23 | — | — | EP | disclosed |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| EP-3375621-A2 | TWO COMPONENT INK JETTABLE PRIMER AND INCORPORATION OF ADHESION PROMOTER TO THE INK FOR PRINTING ONTO 3D OBJECTS | Xerox Corporation (US) | 2018-09-19 | — | — | EP | disclosed |
| US-10071095-B2 | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of neurological and psychiatric disorders | Janssen Pharmaceuticals, Inc. (US) | 2018-09-11 | — | — | US | disclosed |
| US-20130197009-A1 | ANTAGONIST FOR MUTANT ANDROGEN RECEPTOR | ASTELLAS PHARMA INC. (JP) | 2013-08-01 | — | — | US | disclosed |
| US-20120184525-A1 | 1,2,3-TRIAZOLO [4,3-A] PYRIDINE DERIVATIVES AND THIER USE FOR THE TREATMENT OF PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | ADDEX PHARMA S.A. (CH) | 2012-07-19 | — | — | US | disclosed |
| CN-102439008-A | 1,2, 3-triazolo [4,3-a ] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders | ORTHO MCNEIL JANSSEN PHARM | 2012-05-02 | — | — | CN | disclosed |
| EP-2430022-A1 | 1,2,3-TRIAZOLO Ý4,3-A¨PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | Janssen Pharmaceuticals, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130424-A9 | 1,2,4-TRIAZOLO [4,3-A] PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2010130424-A1 | 1,2,3-TRIAZOLO [4,3-A] PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2010-11-18 | — | — | WO | disclosed |
| EP-1075469-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-02-14 | — | — | EP | disclosed |
| WO-2000052001-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-09-08 | — | — | WO | disclosed |
| US-4925848-A | ANALGESICS, SIDE EFFECT REDUCTION | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0295783-A2 | A derivative of codeine | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | ADRB1 4438/4885SIGMAR1 1261/4885HTR3E 2611/4885 |
| US-10071095-B2 | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of neurological and psychiatric disorders | GRM2, GRM1, GRIA2 | ADRB1 248/4885SIGMAR1 334/4885HTR3E 150/4885 |
| US-20130197009-A1 | ANTAGONIST FOR MUTANT ANDROGEN RECEPTOR | AR, NR5A1, NR5A2 | ADRB1 73/4885SIGMAR1 1482/4885HTR3E 1053/4885 |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | ADRB1 4438/4885SIGMAR1 1261/4885HTR3E 2611/4885 |
| US-20120184525-A1 | 1,2,3-TRIAZOLO [4,3-A] PYRIDINE DERIVATIVES AND THIER USE FOR THE TREATMENT OF PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GRM2, GRM3, GRM1 | ADRB1 249/4885SIGMAR1 330/4885HTR3E 98/4885 |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | ADRB1 4438/4885SIGMAR1 1261/4885HTR3E 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.