Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527963 | 0.81 | P4HTM (0.60) | P4HTMTRPC6MAP4K4PTGER1FOLH1 | |
| Hydrochloric Acid SCHEMBL10666309 | 0.80 | P4HTM (0.59) | P4HTMMAP4K4PTGER1FOLH1MCL1 | |
| SCHEMBL31056250 | 0.80 | PTGER1 (0.48) | PTGER1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31056217 | 0.78 | FOLH1 (0.48) | PTGER1PKMFOLH1MCL1KDM4E | |
| SCHEMBL31056459 | 0.78 | FOLH1 (0.45) | PTGER1NPC1FOLH1MCL1KDM4E | |
| SCHEMBL31056825 | 0.78 | MCL1 (0.47) | PTGER1FOLH1MCL1KDM4E | |
| SCHEMBL31056045 | 0.78 | PTGER1 (0.50) | PTGER1NPC1RAB9AFOLH1MCL1 | |
| SCHEMBL21045862 | 0.77 | TRPC6 (0.55) | P4HTMTRPC6NPC1PKMRAB9A | |
| SCHEMBL31055879 | 0.77 | P4HTM (0.46) | P4HTMPTGER1FOLH1MCL1 | |
| SCHEMBL31056247 | 0.75 | FOLH1 (0.43) | PTGER1FOLH1MCL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |