Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056217 | 0.89 | FOLH1 (0.48) | PKMTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL31056326 | 0.88 | RAB9A (0.44) | LMNAHPGDNPC1PKMRAB9A | |
| SCHEMBL31056342 | 0.87 | ALDH1A1 (0.47) | LMNAHPGDNPC1PKMRAB9A | |
| SCHEMBL17782343 | 0.83 | SMPD1 (0.53) | LMNAHPGDSMPD1HDAC1HDAC8 | |
| SCHEMBL31056108 | 0.82 | HPGD (0.50) | LMNAHPGDNPC1PKMRAB9A | |
| SCHEMBL16101085 | 0.81 | CTSV (0.49) | LMNAHPGDNPC1SMPD1HDAC1 | |
| SCHEMBL24057095 | 0.80 | SMPD1 (0.56) | LMNAHPGDNPC1RAB9ASMPD1 | |
| SCHEMBL30577381 | 0.80 | SMPD1 (0.56) | LMNAHPGDNPC1RAB9ASMPD1 | |
| SCHEMBL18690310 | 0.80 | SMPD1 (0.56) | LMNAHPGDNPC1RAB9ASMPD1 | |
| SCHEMBL31056825 | 0.79 | MCL1 (0.47) | TDP1L3MBTL1FOLH1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |