Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.30 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058752 | 0.74 | KDM4E (0.50) | ALDH1A1KDM4ERXFP1CDK2POLA1 | |
| SCHEMBL2640836 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KDM4ERXFP1CDK2POLA1 | |
| SCHEMBL3578267 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KDM4ERXFP1CDK2POLA1 | |
| SCHEMBL2640835 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4ERXFP1CDK2POLA1 | |
| SCHEMBL5033486 | 0.69 | CDK2 (0.49) | ALDH1A1KDM4ERXFP1CDK2PAK1 | |
| SCHEMBL10694875 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KDM4ERXFP1CDK2POLA1 | |
| SCHEMBL11200783 | 0.67 | ALDH1A1 (0.58) | ALDH1A1KDM4ERXFP1CDK2POLA1 | |
| Iodide SCHEMBL28673351 | 0.67 | ALDH1A1 (0.53) | ALDH1A1KDM4ERXFP1CDK2POLA1 | |
| SCHEMBL8741748 | 0.67 | KDM4E (0.49) | ALDH1A1KDM4ERXFP1CDK2POLA1 | |
| SCHEMBL10552261 | 0.67 | KDM4E (0.45) | ALDH1A1KDM4ERXFP1CDK2POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323356-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | FUNDACIO INST DE RECERCA BIOMEDICA IRB BARCELONA (ES) | 2023-10-12 | — | — | US | disclosed |
| US-11591599-B2 | Method for the diagnosis, prognosis and treatment of cancer metastasis | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2023-02-28 | — | — | US | disclosed |
| US-20190309299-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) (ES) | 2019-10-10 | — | — | US | disclosed |
| US-20170002357-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | FUNDACIÓ INST DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2017-01-05 | — | — | US | disclosed |
| US-20160040247-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS, AND TRATMENT OF CANCER METASTASIS | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2016-02-11 | — | — | US | disclosed |
| US-20140314792-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140314792-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | MAFG, RHOXF2, MAFK | ALDH1A1 3426/4885KDM4E 2686/4885RXFP1 690/4885 |
| US-20230323356-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | MAFG, RHOXF2, MAFK | ALDH1A1 3426/4885KDM4E 2686/4885RXFP1 690/4885 |
| US-20170002357-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | MAFG, RHOXF2, MAFK | ALDH1A1 3426/4885KDM4E 2686/4885RXFP1 690/4885 |
| US-11591599-B2 | Method for the diagnosis, prognosis and treatment of cancer metastasis | MAFG, RHOXF2, MAFK | ALDH1A1 3426/4885KDM4E 2686/4885RXFP1 690/4885 |
| US-20190309299-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | MAFG, RHOXF2, MAFK | ALDH1A1 3426/4885KDM4E 2686/4885RXFP1 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.