SCHEMBL3105989

SCHEMBL3105989

CCC(C)[Zn]C(C)CC.OP(O)(=S)S

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3105983 0.90 TSHR (0.33) TSHR
SCHEMBL3094871 0.81 FDPS (0.34) TSHR
Phosphoric Acid SCHEMBL27928113 0.79 LAP3 (0.40) TSHR
SCHEMBL3100747 0.78 FDPS (0.39)
SCHEMBL3029263 0.78
SCHEMBL28109890 0.74 TSHR (0.35) TSHR
SCHEMBL3094844 0.73
SCHEMBL29065588 0.70 MMP1 (0.40) TSHR
Isopropyl Alcohol SCHEMBL29005154 0.68 ALDH1A1 (0.46)
SCHEMBL28946391 0.67 ALPG (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1780257-B1 USE OF LUBRICANT COMPOSITIONS IDEMITSU KOSAN CO (JP) 2018-06-13 EP disclosed
CN-104955984-B Sliding member and method for manufacturing same 日产自动车株式会社 2018-06-12 CN disclosed
CN-105087110-B Lubricant oil composite 吉坤日矿日石能源株式会社 2018-04-27 CN disclosed
CN-107075402-A Lubricant oil composite 国际壳牌研究有限公司 2017-08-18 CN disclosed
CN-107001972-A Lubricating oil composition for internal combustion engine 国际壳牌研究有限公司 2017-08-01 CN disclosed
CN-105980533-A Tractor hydraulic fluid composition 雪佛龙奥伦耐有限责任公司 2016-09-28 CN disclosed
CN-103261385-B Gear oil composition JX NIPPON OIL & ENERGY CORP. (JP) 2016-05-25 CN disclosed
CN-105087110-A Lubricating oil composition JX NIPPON OIL & ENERGY CORP 2015-11-25 CN disclosed
CN-104946353-A Lubricating oil composition JX NIPPON OIL & ENERGY CORP 2015-09-30 CN disclosed
CN-103003402-B Lubricating oil composition for low-friction sliding material and sliding mechanism using same IDEMITSU KOSAN CO.,LTD. (JP) 2015-09-09 CN disclosed
CN-102177227-B Lubricant composition and method for producing same JX NIPPON OIL & ENERGY CORP 2013-12-18 CN disclosed
CN-103003402-A Lubricating oil composition for low-friction sliding material and sliding mechanism using same IDEMITSU KOSAN CO 2013-03-27 CN disclosed
CN-101760286-B Low-friction sliding mechanism, low-friction agent composition, and method for reducing friction NIPPON OIL CORP 2013-03-20 CN disclosed
US-7803745-B2 Lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2010-09-28 US disclosed
US-20080096775-A1 Lubricant Composition IDEMITSU KOSAN CO., LTD. (JP) 2008-04-24 US disclosed
EP-1780257-A1 LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2007-05-02 EP disclosed
EP-0397507-B1 Silicone fluids for viscous couplings TONEN CORP (JP) 1995-03-15 EP disclosed
US-5332515-A Polysiloxane, phosphorus type anti-wear agent TONEN CORPORATION (JP) 1994-07-26 US disclosed
US-5132031-A Antiwear Agents, Antioxidants INSTITUT FRANCAIS DU PETROLE (FR) 1992-07-21 US disclosed
EP-0397507-A1 Silicone fluids for viscous couplings Tonen Corporation (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080096775-A1 Lubricant Composition ELOVL6, ELOVL5, ASH2L TSHR 4781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.