Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955804 | 0.88 | LMNA (0.60) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL10617286 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL5166558 | 0.79 | SMN1; SMN2 (0.75) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL10621796 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11068950 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL6958448 | 0.76 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL28410690 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL15976546 | 0.74 | ALDH1A1 (1.00) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL9235617 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL4838616 | 0.73 | SMN1; SMN2 (0.97) | SMN1; SMN2LMNAMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662202-A1 | PYRIDINE AND DIHYDROPYRIDINE COMPOUNDS AND USES THEREOF | Clark Atlanta University, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024167861-A1 | PYRIDINE AND DIHYDROPYRIDINE COMPOUNDS AND USES THEREOF | CLARK ATLANTA UNIVERSITY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |