Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26270707 | 0.85 | MTNR1B (0.64) | MTNR1BALDH1A1L3MBTL1LMNAKDM4E | |
| SCHEMBL31060091 | 0.81 | MTNR1B (0.53) | MTNR1BALDH1A1L3MBTL1LMNAMTNR1A | |
| SCHEMBL31060099 | 0.79 | MTNR1B (0.48) | MTNR1BALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL31060090 | 0.78 | MTNR1B (0.46) | MTNR1BALDH1A1L3MBTL1LMNAMTNR1A | |
| SCHEMBL17662315 | 0.76 | KMT2A (0.60) | ALDH1A1L3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL31522180 | 0.76 | MTNR1B (0.50) | MTNR1BALDH1A1L3MBTL1LMNAKDM4E | |
| SCHEMBL15145782 | 0.74 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL38663449 | 0.73 | HDAC1 (0.48) | ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL26270737 | 0.73 | ALDH1A1 (0.51) | MTNR1BALDH1A1L3MBTL1LMNAMTNR1A | |
| SCHEMBL20514222 | 0.71 | PKM (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546074-A | Deuterated proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-08-27 | — | — | CN | disclosed |