Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666151 | 0.88 | MTNR1B (0.63) | MTNR1BPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30567101 | 0.88 | MTNR1B (0.63) | MTNR1BPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31120712 | 0.83 | MTNR1B (0.53) | MTNR1BPOLBAURKAMETKDR | |
| SCHEMBL18666149 | 0.79 | ALDH1A1 (0.55) | MTNR1BPOLBMEN1KMT2ALMNA | |
| SCHEMBL31060089 | 0.79 | MTNR1B (0.46) | MTNR1BPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL31522175 | 0.78 | MTNR1B (0.56) | MTNR1BPOLBAURKAMETKDR | |
| SCHEMBL31060091 | 0.78 | MTNR1B (0.53) | MTNR1BPOLBKMT2ASMN1; SMN2LMNA | |
| SCHEMBL18666146 | 0.77 | ADRA2C (0.54) | MTNR1BPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29660113 | 0.77 | ADRA2C (0.54) | MTNR1BPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18666150 | 0.77 | MTNR1B (0.47) | MTNR1BMAPTKDM4ERECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546074-A | Deuterated proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-08-27 | — | — | CN | disclosed |