Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522182 | 0.94 | POLB (0.44) | MTNR1BALDH1A1KMT2APKMLMNA | |
| SCHEMBL26270707 | 0.89 | MTNR1B (0.64) | MTNR1BALDH1A1KMT2APKMLMNA | |
| SCHEMBL31522156 | 0.82 | LMNA (0.43) | MTNR1BALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31522153 | 0.80 | ADRA2C (0.65) | MTNR1BALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL21581622 | 0.79 | GRM5 (0.40) | MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL17414151 | 0.78 | LPAR1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL25388312 | 0.77 | MTNR1B (0.70) | MTNR1BALDH1A1KMT2APKMLMNA | |
| SCHEMBL31522178 | 0.77 | MTNR1B (0.50) | MTNR1BALDH1A1KMT2APKMLMNA | |
| SCHEMBL31060089 | 0.76 | MTNR1B (0.46) | MTNR1BALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL15145782 | 0.75 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TSHRL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054318-A1 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2025-03-13 | — | — | WO | disclosed |