Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 6/20 | 0.84 |
| ▸ | CASP3 | P42574 | 6/20 | 0.72 |
| ▸ | CASP1 | P29466 | 2/20 | 0.64 |
| ▸ | CASP9 | P55211 | 2/20 | 0.64 |
| ▸ | CASP4 | P49662 | 1/20 | 0.64 |
| ▸ | CASP5 | P51878 | 1/20 | 0.64 |
| ▸ | CASP6 | P55212 | 1/20 | 0.64 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.64 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.64 |
| ▸ | CTSB | P07858 | 5/20 | 0.61 |
| ▸ | CTSK | P43235 | 4/20 | 0.61 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.54 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490629 | 0.88 | PSMB5 (0.73) | PSMB5CASP3CASP1CASP9CTSB | |
| SCHEMBL19944919 | 0.85 | CASP3 (0.70) | PSMB5CASP3CASP1CASP9CASP4 | |
| SCHEMBL8259042 | 0.83 | CTSL (0.70) | PSMB5CASP3CASP1CASP9CTSB | |
| SCHEMBL8260299 | 0.82 | CTSL (0.71) | PSMB5CASP3CTSBCTSLCASP7 | |
| SCHEMBL15926429 | 0.82 | CTSB (0.65) | PSMB5CASP3CTSBCTSKCTSL | |
| SCHEMBL14148468 | 0.82 | CTSB (0.65) | PSMB5CASP3CTSBCTSKCTSL | |
| SCHEMBL23644903 | 0.81 | PSMB5 (0.63) | PSMB5CASP3CASP1CASP9CASP4 | |
| SCHEMBL8260998 | 0.81 | CTSL (0.69) | PSMB5CASP3CASP1CASP9CTSB | |
| SCHEMBL15462675 | 0.80 | CASP3 (0.90) | PSMB5CASP3CASP1CASP9CASP4 | |
| SCHEMBL22697479 | 0.80 | CASP3 (0.63) | PSMB5CASP3CTSBCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |