Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 10/20 | 0.70 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.69 |
| ▸ | CASP7 | P55210 | 6/20 | 0.67 |
| ▸ | CASP1 | P29466 | 5/20 | 0.67 |
| ▸ | CASP9 | P55211 | 2/20 | 0.67 |
| ▸ | CASP4 | P49662 | 1/20 | 0.66 |
| ▸ | CTSL | P07711 | 2/20 | 0.63 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490629 | 0.90 | PSMB5 (0.73) | CASP3PSMB5CASP7CASP1CASP9 | |
| SCHEMBL18472716 | 0.89 | CASP3 (0.84) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL8260299 | 0.88 | CTSL (0.71) | CASP3PSMB5CASP7CTSLCTSB | |
| SCHEMBL15462665 | 0.87 | CASP3 (0.93) | CASP3PSMB5CASP7CASP1CASP9 | |
| SCHEMBL8259042 | 0.87 | CTSL (0.70) | CASP3PSMB5CASP7CASP1CASP9 | |
| SCHEMBL19944650 | 0.86 | CASP3 (0.66) | CASP3PSMB5CASP7CASP1CASP9 | |
| SCHEMBL31060320 | 0.85 | PSMB5 (0.84) | CASP3PSMB5CASP7CASP1CASP9 | |
| SCHEMBL19944654 | 0.85 | CASP1 (0.66) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL8260998 | 0.84 | CTSL (0.69) | CASP3PSMB5CASP7CASP1CASP9 | |
| SCHEMBL7888495 | 0.84 | CASP3 (0.90) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |