Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.66 |
| ▸ | AURKA | O14965 | 3/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | IKBKB | O14920 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.62 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.62 |
| ▸ | PRKCG | P05129 | 1/20 | 0.62 |
| ▸ | CDK1 | P06493 | 1/20 | 0.62 |
| ▸ | LYN | P07948 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KIT | P10721 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.62 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.62 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | MARK3 | P27448 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695715 | 0.89 | AURKB (0.66) | MAPK8AURKACHEK1IKBKBNPC1 | |
| SCHEMBL29695718 | 0.87 | AURKA (0.64) | MAPK8AURKACHEK1IKBKBNPC1 | |
| SCHEMBL28392412 | 0.82 | MAPK8 (0.51) | MAPK8AURKACHEK1IKBKBNPC1 | |
| SCHEMBL27109893 | 0.79 | GPR39 (0.58) | MAPK8CDK1CDK2KDM4EGAA | |
| SCHEMBL440486 | 0.78 | AURKA (1.00) | MAPK8AURKACHEK1IKBKBNPC1 | |
| SCHEMBL25607003 | 0.77 | GPR39 (0.56) | MAPK8CDK1CDK2KDM4EGAA | |
| SCHEMBL14537547 | 0.76 | MAPK8 (0.47) | MAPK8AURKACDK1CDK2KDM4E | |
| SCHEMBL1033751 | 0.75 | CTSK (0.60) | MAPK8CHEK1IKBKBPRKCGCDK1 | |
| SCHEMBL18920813 | 0.75 | CTSK (0.60) | MAPK8CHEK1IKBKBPRKCGCDK1 | |
| SCHEMBL14024765 | 0.75 | CDC7 (0.57) | MAPK8AURKACDK1CDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |