Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063282 | 0.82 | MAPT (0.38) | P2RX3LMNAKMT2AALDH1A1MAPK1 | |
| SCHEMBL29241474 | 0.78 | S100B (0.42) | P2RX3LMNAKMT2ANFKB1NFKB2 | |
| SCHEMBL25213314 | 0.75 | CYP3A4 (0.43) | P2RX3KMT2ANFKB1NFKB2RELA | |
| SCHEMBL5906809 | 0.74 | P2RX3 (0.43) | P2RX3LMNAKMT2ANFKB1NFKB2 | |
| SCHEMBL2325513 | 0.72 | HPGD (0.36) | P2RX3LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL6213093 | 0.72 | F2 (0.44) | P2RX3LMNANFKB1NFKB2RELA | |
| SCHEMBL30060460 | 0.71 | ALDH1A1 (0.37) | P2RX3LMNAKMT2ANFKB1NFKB2 | |
| SCHEMBL6612961 | 0.71 | ABCB1 (0.36) | LMNAKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL23611364 | 0.71 | ALDH1A1 (0.37) | P2RX3LMNAKMT2ANFKB1NFKB2 | |
| SCHEMBL13248101 | 0.71 | NFKB1 (0.37) | P2RX3KMT2ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |