Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3124079 | 0.88 | TACR1 (0.43) | TACR1ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL3124239 | 0.88 | ALDH1A1 (0.50) | CHRM2CHRM3ALDH1A1KMT2ALMNA | |
| SCHEMBL3114910 | 0.87 | TACR1 (0.54) | TACR1ALDH1A1TSHRLMNATP53 | |
| SCHEMBL3122228 | 0.86 | TACR1 (0.50) | TACR1ALDH1A1LMNATP53SLC6A4 | |
| SCHEMBL3112449 | 0.82 | SLC6A3 (0.49) | CHRM2CHRM3ALDH1A1LMNATP53 | |
| SCHEMBL3121674 | 0.82 | OPRM1 (0.39) | TACR1ALDH1A1LMNATP53SLC6A4 | |
| SCHEMBL926471 | 0.77 | SLC6A4 (0.51) | TACR1CHRM3SLC6A4MAOAMAOB | |
| SCHEMBL3108478 | 0.77 | OPRD1 (0.55) | CHRM2CHRM3ALDH1A1MAPTKMT2A | |
| SCHEMBL3119135 | 0.77 | CHRM3 (0.50) | CHRM2CHRM3ALDH1A1KMT2AMAOA | |
| SCHEMBL11466331 | 0.76 | TACR1 (0.50) | TACR1CHRM2CHRM3LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179118-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-15 | — | — | US | disclosed |
| EP-2060563-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179118-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | HRH2, HRH1, HRH4 | TACR1 190/4885CHRM2 22/4885CHRM3 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.