Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112449 | 0.94 | SLC6A3 (0.49) | ALDH1A1LMNATP53CHRM3CHRM2 | |
| SCHEMBL3119135 | 0.89 | CHRM3 (0.50) | ALDH1A1CHRM3CHRM2OPRM1SIGMAR1 | |
| SCHEMBL3108478 | 0.88 | OPRD1 (0.55) | ALDH1A1CHRM3CHRM2OPRM1SIGMAR1 | |
| SCHEMBL3106409 | 0.88 | TACR1 (0.44) | ALDH1A1LMNATP53CHRM3CHRM2 | |
| SCHEMBL3124079 | 0.88 | TACR1 (0.43) | ALDH1A1LMNATP53MEN1KMT2A | |
| SCHEMBL3114898 | 0.88 | MEN1 (0.52) | ALDH1A1CHRM3CHRM2OPRM1SIGMAR1 | |
| SCHEMBL3119758 | 0.88 | MEN1 (0.52) | ALDH1A1CHRM3CHRM2OPRM1SIGMAR1 | |
| SCHEMBL3114910 | 0.87 | TACR1 (0.54) | ALDH1A1LMNATP53OPRM1CHRM1 | |
| SCHEMBL3122228 | 0.86 | TACR1 (0.50) | ALDH1A1LMNATP53OPRM1 | |
| SCHEMBL3109359 | 0.85 | OPRM1 (0.51) | CHRM3CHRM2OPRM1SIGMAR1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179118-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-15 | — | — | US | disclosed |
| EP-2060563-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179118-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | HRH2, HRH1, HRH4 | ALDH1A1 618/4885LMNA 3236/4885TP53 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.