Sugi Predict

Sugi Predict / Compounds / SCHEMBL310695

SCHEMBL310695

SCHEMBL310695

Cc1ccc(S(=O)(=O)c2[c]cccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.54
▸ HTT P42858 2/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ RAPGEF4 Q8WZA2 1/20 0.43
▸ ALDH1A1 P00352 3/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ BCHE P06276 1/20 0.41
▸ ACHE P22303 1/20 0.41
▸ CA12 O43570 3/20 0.41
▸ CA9 Q16790 3/20 0.41
▸ CA1 P00915 3/20 0.41
▸ CA2 P00918 3/20 0.41
▸ CA3 P07451 1/20 0.41
▸ CA6 P23280 1/20 0.41
▸ CA5A P35218 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ CA5B Q9Y2D0 1/20 0.41
▸ C5AR1 P21730 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL315684 0.84 HTR6 (0.54) GAASMN1; SMN2ALDH1A1KMT2ACA12
SCHEMBL10438578 0.81 PTGS2 (0.40) HTTSMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL6661818 0.81 HTR6 (0.39) KMT2A
SCHEMBL10438542 0.81 KMT2A (0.44) GAAHTTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL10882944 0.80 MEN1 (0.43) GAAHTTALDH1A1KMT2AMEN1
SCHEMBL150811 0.80 HTR6 (0.38) GAAKMT2AMEN1CA9CA1
SCHEMBL8046870 0.78 GAA (0.50) GAAHTTSMN1; SMN2RAPGEF4ALDH1A1
SCHEMBL1982254 0.78 GAA (0.54) GAAHTTSMN1; SMN2RAPGEF4ALDH1A1
SCHEMBL971359 0.77 CA2 (0.46) GAAHTTALDH1A1KMT2AMEN1
SCHEMBL8058723 0.76 GAA (0.57) GAAHTTSMN1; SMN2RAPGEF4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021016814-A1 LUMINESCENT GOLD (III) COMPOUND, METHOD FOR PREPARING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-02-04 — — WO claimed
US-5270308-A Hypotensives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-12-14 — — US claimed
CN-114206886-B Gold (III) compound, method for preparing the same, and organic light emitting device using the same 广东聚华印刷显示技术有限公司 2024-02-27 — — CN disclosed
US-20230265087-A1 SMALL MOLECULE ACTIVATORS OF TIE-2 EyePoint, Inc. 2023-08-24 — — US disclosed
US-20230094176-A1 COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS CERENO SCIENT AB (SE) 2023-03-30 — — US disclosed
US-11613534-B2 Small molecule activators of Tie-2 EyePoint Pharmaceuticals, Inc. (US) 2023-03-28 — — US disclosed
CN-114206886-A Luminescent gold (III) compound, method for preparing same, and organic light emitting device using same 广东聚华印刷显示技术有限公司 2022-03-18 — — CN disclosed
US-20210147404-A1 SMALL MOLECULE ACTIVATORS OF TIE-2 EyePoint, Inc. 2021-05-20 — — US disclosed
WO-2021086904-A1 SMALL MOLECULE ACTIVATORS OF TIE-2 Aerpio Pharmaceuticals, Inc. (US) 2021-05-06 — — WO disclosed
US-20210060014-A1 COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS CERENO SCIENTIFIC AB (SE) 2021-03-04 — — US disclosed
WO-2021016814-A1 LUMINESCENT GOLD (III) COMPOUND, METHOD FOR PREPARING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-02-04 — — WO disclosed
US-6552065-B2 Antiproliferative agents NOVARTIS AG (CH) 2003-04-22 — — US disclosed
US-20030018062-A1 Deacetylase inhibitors SECURA BIO, INC. 2003-01-23 — — US disclosed
WO-2002022577-A2 HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS NOVARTIS AG (CH) 2002-03-21 — — WO disclosed
EP-0714907-A1 Oligoribonucleotides with amide backbone F. HOFFMANN-LA ROCHE AG (CH) 1996-06-05 — — EP disclosed
US-5270308-A Hypotensives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-12-14 — — US disclosed
EP-0351332-B1 HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM RHONE-POULENC AGROCHIMIE (FR) 1993-03-24 — — EP disclosed
EP-0477789-A1 1,3-Benzoxazine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1992-04-01 — — EP disclosed
EP-0351332-A1 Herbicidal compounds and compositions containing them RHONE-POULENC AGROCHIMIE (FR) 1990-01-17 — — EP disclosed
US-4198205-A SULFONIC ACID-FREE DISPERSE DYES BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147404-A1 SMALL MOLECULE ACTIVATORS OF TIE-2 TIE1, TEK, KDR GAA 4631/4885HTT 2750/4885SMN1; SMN2 4549/4885
US-11613534-B2 Small molecule activators of Tie-2 TIE1, TEK, KDR GAA 4631/4885HTT 2750/4885SMN1; SMN2 4549/4885
US-20230265087-A1 SMALL MOLECULE ACTIVATORS OF TIE-2 TIE1, TEK, KDR GAA 4631/4885HTT 2750/4885SMN1; SMN2 4549/4885
US-20210060014-A1 COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS HDAC3, HDAC1, HDAC2 GAA 1052/4885HTT 546/4885SMN1; SMN2 2901/4885
US-20230094176-A1 COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS HDAC3, HDAC2, HDAC1 GAA 1104/4885HTT 587/4885SMN1; SMN2 3053/4885
US-20030018062-A1 Deacetylase inhibitors HDAC1, HDAC3, HDAC6 GAA 243/4885HTT 301/4885SMN1; SMN2 3167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.