SCHEMBL8046870

SCHEMBL8046870

Cc1ccc(S(=O)(=O)c2[c]ccc(S(=O)(=O)c3ccccc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
HTT P42858 2/20 0.49
ALDH1A1 P00352 4/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 1/20 0.44
HTR6 P50406 4/20 0.44
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8058723 0.94 GAA (0.57) GAASMN1; SMN2HTTALDH1A1MAPT
SCHEMBL8046992 0.90 HTR6 (0.54) GAASMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL8059424 0.85 ALDH1A1 (0.47) GAASMN1; SMN2HTTALDH1A1MAPT
SCHEMBL9319768 0.82 HTR6 (0.43) GAASMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL9322085 0.82 HTR6 (0.48) GAASMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL1982254 0.82 GAA (0.54) GAASMN1; SMN2HTTALDH1A1MAPT
SCHEMBL891138 0.79 GAA (0.80) GAASMN1; SMN2HTTALDH1A1MAPT
SCHEMBL8046897 0.79 LMNA (0.47) GAASMN1; SMN2HTTALDH1A1MAPT
SCHEMBL310695 0.78 GAA (0.54) GAASMN1; SMN2HTTALDH1A1MAPT
SCHEMBL7528632 0.78 GAA (0.48) GAASMN1; SMN2HTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed