SCHEMBL8058723

SCHEMBL8058723

Cc1ccc(S(=O)(=O)c2[c]ccc(S(=O)(=O)c3ccc(C)cc3)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.57
RAPGEF4 Q8WZA2 1/20 0.46
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.42
HTT P42858 2/20 0.42
CA2 P00918 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PKM P14618 1/20 0.41
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA3 P07451 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA5B Q9Y2D0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046870 0.94 GAA (0.50) GAARAPGEF4KMT2AALDH1A1MAPT
SCHEMBL1982254 0.87 GAA (0.54) GAARAPGEF4KMT2AALDH1A1MAPT
SCHEMBL8046897 0.84 LMNA (0.47) GAARAPGEF4KMT2AALDH1A1MAPT
SCHEMBL7528632 0.83 GAA (0.48) GAARAPGEF4KMT2AALDH1A1MAPT
SCHEMBL8059405 0.82 ALDH1A1 (0.57) GAAKMT2AALDH1A1MAPTMEN1
SCHEMBL8046992 0.81 HTR6 (0.54) GAAKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL7825028 0.80 GAA (0.46) GAARAPGEF4KMT2AALDH1A1MAPT
SCHEMBL8059424 0.79 ALDH1A1 (0.47) GAAKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL8061637 0.78 KMT2A (0.42) GAARAPGEF4KMT2AALDH1A1MAPT
SCHEMBL310696 0.77 GAA (0.73) GAARAPGEF4KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed