Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
| ▸ | ICMT | O60725 | 4/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31083752 | 0.90 | KIF11 (0.49) | KIF11ICMTNR4A2IDO1HTR6 | |
| SCHEMBL31070623 | 0.89 | ECE1 (0.40) | KIF11NR4A2CDK4CCND1KDM4E | |
| SCHEMBL31070544 | 0.88 | ICMT (0.43) | ICMTIDO1ALDH1A1 | |
| SCHEMBL31070518 | 0.88 | KIF11 (0.43) | KIF11ICMTNR4A2IDO1HTR6 | |
| SCHEMBL31070662 | 0.88 | IDO1 (0.38) | ICMTNR4A2IDO1HTR6NOS1 | |
| SCHEMBL31070497 | 0.87 | NR4A2 (0.42) | ICMTNR4A2HTR6NOS1 | |
| SCHEMBL31070564 | 0.85 | IDO1 (0.35) | KIF11ICMTNR4A2IDO1HTR6 | |
| SCHEMBL31070513 | 0.83 | KIF11 (0.41) | KIF11ICMTNR4A2IDO1CDK4 | |
| SCHEMBL31070522 | 0.82 | HSD11B1 (0.42) | KIF11CDK4CCND1KDM4EMEN1 | |
| SCHEMBL31070637 | 0.81 | IMPDH2 (0.38) | KIF11CDK4CCND1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |