SCHEMBL310707

SCHEMBL310707

CC(C)(C)c1cc(Br)cc(C=O)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 7/20 0.58
GABBR2 O75899 1/20 0.43
GABBR1 Q9UBS5 1/20 0.43
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 2/20 0.42
USP2 O75604 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
BLM P54132 1/20 0.42
ATM Q13315 1/20 0.42
HIF1A Q16665 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CA2 P00918 3/20 0.42
CA1 P00915 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31345777 1.00 ERN1 (0.58) ERN1GABBR2GABBR1ALDH1A1MEN1
SCHEMBL10323583 0.81 ERN1 (0.58) ERN1
SCHEMBL29592823 0.81 ERN1 (0.58) ERN1
SCHEMBL30222051 0.81 ERN1 (0.47) ERN1GABBR2GABBR1ALDH1A1MEN1
SCHEMBL207854 0.81 ERN1 (0.47) ERN1GABBR2GABBR1ALDH1A1MEN1
SCHEMBL544809 0.80 ERN1 (0.78) ERN1CYP3A4TSHR
SCHEMBL49614 0.80 CA2 (0.64) GABBR2GABBR1ALDH1A1MEN1KMT2A
SCHEMBL30646074 0.79 ERN1 (0.67) ERN1GABBR2GABBR1ALDH1A1MEN1
SCHEMBL29467330 0.79 ALOX5 (0.49) ERN1GABBR2GABBR1ALDH1A1MEN1
SCHEMBL187267 0.79 ALOX5 (0.49) ERN1GABBR2GABBR1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036813-A Schiff base cobalt complex, preparation method and application 安徽大学 2026-05-15 CN claimed
CN-115894347-B Tetranuclear cobalt complex based on Salen ligand, preparation method and application thereof 广西师范大学 2025-03-21 CN claimed
CN-115894347-A Salen ligand-based tetranuclear cobalt complex, and preparation method and application thereof 广西师范大学 2023-04-04 CN claimed
CN-101270112-A Preparation of polymerization type chiral catalyst, preparation and application of cyclic carbonates with optical activity UNIV LANZHOU (CN) 2008-09-24 CN claimed
CN-122036813-A Schiff base cobalt complex, preparation method and application 安徽大学 2026-05-15 CN disclosed
CN-122036813-A Schiff base cobalt complex, preparation method and application 安徽大学 2026-05-15 CN disclosed
CN-115894347-B Tetranuclear cobalt complex based on Salen ligand, preparation method and application thereof 广西师范大学 2025-03-21 CN disclosed
CN-117777327-A Manganese-based catalyst, preparation method and application 铜仁学院 2024-03-29 CN disclosed
CN-115894347-A Salen ligand-based tetranuclear cobalt complex, and preparation method and application thereof 广西师范大学 2023-04-04 CN disclosed
CN-115894950-A Pyrazole functionalized metal-salen-based chiral MOFs and preparation method thereof 嘉兴学院 2023-04-04 CN disclosed
EP-2618662-B1 SYNTHESIS OF SUBSTITUTED SALICYLALDEHYDE DERIVATIVES SAUDI ARAMCO TECH CO (SA) 2019-11-06 EP disclosed
US-10040800-B2 Synthesis of substituted salicylaldehyde derivatives SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-08-07 US disclosed
US-20050004204-A1 2-Iminopyrrolidine derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2005-01-06 US disclosed
CN-1503784-A 2-iminopyrrolidine derivatives ������������ʽ���� 2004-06-09 CN disclosed
EP-1391451-A1 2-IMINOPYRROLIDINE DERIVATES Eisai Co., Ltd. (JP) 2004-02-25 EP disclosed
EP-1343740-A1 PROCESS FOR OLIGOMERISING OR POLYMERISING ETHYLENE Univation Technologies LLC (US) 2003-09-17 EP disclosed
US-20030105250-A1 Olefin oligomerization catalysts, their production and use WHITEKER GREGORY T (US) 2003-06-05 US disclosed
US-6531555-B2 Using phenoxide/transition metal complexes and activator compound for polymerization of ethylene UNIVATION TECHNOLOGIES, LLP 2003-03-11 US disclosed
WO-2002049995-A1 PROCESS FOR OLIGOMERISING OR POLYMERISING ETHYLENE UNIVATION TECHNOLOGIES, LLC (US) 2002-06-27 WO disclosed
US-20020077431-A1 Olefin oligomerization catalysts, their production and use UNIVATION TECHNOLOGIES, LLC 2002-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004204-A1 2-Iminopyrrolidine derivatives H1-2, H1-3, H1-0 ERN1 3042/4885GABBR2 1753/4885GABBR1 1658/4885
US-10040800-B2 Synthesis of substituted salicylaldehyde derivatives ADSL, ALDH3A1, SUCLA2 ERN1 3530/4885GABBR2 2277/4885GABBR1 2389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.