SCHEMBL31073333

SCHEMBL31073333

CC(C)(C)[Si](C)(C)OCc1ccc(N2CCC(c3ccc(N)nc3)CC2)nc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.35
TRPC6 Q9Y210 2/20 0.35
DRD2 P14416 3/20 0.33
DRD3 P35462 3/20 0.33
LCAT P04180 2/20 0.33
TNKS O95271 1/20 0.33
DRD4 P21917 1/20 0.33
PANK3 Q9H999 1/20 0.33
ACACB O00763 1/20 0.33
CHIA Q9BZP6 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
KLKB1 P03952 1/20 0.32
AOC3 Q16853 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31073086 0.88 TRPC6 (0.36) DGAT1TRPC6DRD2DRD3TNKS
SCHEMBL31072985 0.83 CCR5 (0.40) TRPC6DRD2DRD3DRD4HRH3
SCHEMBL31073153 0.83 DHFR (0.34) DGAT1TRPC6DRD2DRD3DRD4
SCHEMBL31073137 0.83 GCK (0.37) DGAT1TRPC6AOC3
SCHEMBL31073024 0.80 TRPC6 (0.37) TRPC6DRD2DRD3TNKSDRD4
SCHEMBL14844157 0.80 HRH3 (0.39) LCATCHIAHRH3AOC3
SCHEMBL31073422 0.79 HRH3 (0.44) DGAT1TRPC6LCATPANK3ACACB
SCHEMBL643187 0.78 GABRP (0.41)
SCHEMBL30423197 0.78 GABRP (0.41)
Hydrochloric Acid SCHEMBL4180933 0.77 GABRP (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173646-A1 CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-08-22 WO disclosed