Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | MTOR | P42345 | 4/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | GCKR | Q14397 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 3/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073086 | 0.94 | TRPC6 (0.36) | DHFRDGAT1GCKGCKRDRD2 | |
| SCHEMBL31073024 | 0.88 | TRPC6 (0.37) | PIK3CAMTORDRD2DRD3DRD4 | |
| SCHEMBL31073262 | 0.88 | HRH3 (0.36) | PIK3CAMTORGPR119AOC3 | |
| SCHEMBL31072986 | 0.85 | KCNH2 (0.41) | — | |
| SCHEMBL31073006 | 0.85 | HRH3 (0.38) | PIK3CAMTORGCKGCKR | |
| SCHEMBL31073285 | 0.84 | GCK (0.38) | DHFRPIK3CAMTORGCKGCKR | |
| SCHEMBL31073333 | 0.83 | DGAT1 (0.35) | DGAT1DRD2DRD3DRD4TRPC6 | |
| SCHEMBL31072985 | 0.83 | CCR5 (0.40) | DRD2DRD3DRD4TRPC6 | |
| SCHEMBL31073487 | 0.83 | POLB (0.47) | GPR119 | |
| SCHEMBL31073195 | 0.81 | PIK3CA (0.40) | PIK3CAMTORGCKGCKRTRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |