SCHEMBL31075804

SCHEMBL31075804

CCc1c(F)cc(C(C)C)cc1B(O)O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EIF4A3 P38919 1/20 0.34
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14404556 0.82 EIF4A3 (0.37) EIF4A3GABRA1GABRB2SHBG
SCHEMBL22304547 0.76 GABRA1 (0.44) EIF4A3GABRA1GABRB2
SCHEMBL31063473 0.75 PTGS2 (0.35) EIF4A3GABRA1GABRB2
SCHEMBL31076106 0.74 ADRB2 (0.36) EIF4A3GABRA1GABRB2
SCHEMBL14434053 0.72 GABRA1 (0.40) EIF4A3GABRA1GABRB2
SCHEMBL31063173 0.71 EIF4A3 (0.34) EIF4A3GABRA1GABRB2
SCHEMBL16379273 0.70 EIF4A3 (0.36) EIF4A3GABRA1GABRB2
SCHEMBL29891145 0.69 TRPA1 (0.41) EIF4A3GABRA1GABRB2
SCHEMBL28654705 0.69 PTGS1 (0.41) EIF4A3SHBG
SCHEMBL14120255 0.69 TRPA1 (0.41) EIF4A3GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665458-A1 INHIBITING ALPHA V BETA8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
WO-2024173572-A1 INHIBITING α vβ8 INTEGRIN MORPHIC THERAPEUTIC, INC. (US) 2024-08-22 WO disclosed