Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10870364 | 0.90 | POLB (0.38) | GAAPOLBL3MBTL1GPR174 | |
| SCHEMBL2153398 | 0.83 | MAPT (0.37) | LMNAHPGDNPSR1POLBGPR174 | |
| SCHEMBL548111 | 0.82 | RAB9A (0.37) | SMN1; SMN2HPGDPOLB | |
| SCHEMBL2248368 | 0.82 | POLB (0.40) | LMNAGAAPOLB | |
| SCHEMBL9181136 | 0.81 | MTNR1A (0.42) | LMNAHPGDGAAGPR174 | |
| SCHEMBL59812 | 0.79 | HTT (0.36) | SMN1; SMN2HPGDGAAPOLB | |
| SCHEMBL7572469 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2LMNAHPGDGAANPSR1 | |
| SCHEMBL6655593 | 0.78 | THRB (0.42) | THRBPOLB | |
| SCHEMBL6551445 | 0.78 | KMT2A (0.56) | POLB | |
| SCHEMBL6552734 | 0.78 | ALDH1A3 (0.53) | SMN1; SMN2LMNAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799844-B2 | Active energy beam-curable composition for optical material | TOAGOSEI CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| US-7754781-B2 | Active energy beam-curable composition | TOAGOSEI CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20080194727-A1 | Active Energy Beam-Curable Composition | TOAGOSEI CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1857469-A1 | ACTIVE ENERGY RAY-CURABLE COMPOSITION | TOAGOSEI CO., LTD. (JP) | 2007-11-21 | — | — | EP | disclosed |
| US-20070043143-A1 | Active energy beam-curable composition for optical material | THOMSON LICENSING (FR) | 2007-02-22 | — | — | US | disclosed |