SCHEMBL7572469

SCHEMBL7572469

C=C(C)COC(C)OC(C)Sc1ccc(Sc2ccc(SC(C)OC(C)OCC(=C)C)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 3/20 0.33
HPGD P15428 2/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
THRB P10828 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7575940 0.87 SMN1; SMN2 (0.36) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL3107707 0.78 SMN1; SMN2 (0.40) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL9849570 0.72 HSD17B10 (0.30)
SCHEMBL3674860 0.72 PKM (0.36) SMN1; SMN2LMNAGAANPSR1L3MBTL1
SCHEMBL3098494 0.69 LMNA (0.32) SMN1; SMN2LMNAHPGD
SCHEMBL10535413 0.68 LMNA (0.38) LMNA
SCHEMBL21143038 0.67 HPGD (0.40) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL2780451 0.66 HPGD (0.38) SMN1; SMN2LMNAHPGDGAANPSR1
SCHEMBL10870364 0.66 POLB (0.38) GAAL3MBTL1
SCHEMBL3687010 0.66 SMN1; SMN2 (0.50) SMN1; SMN2LMNAHPGDGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795765-B1 Photopolymerizable composition and transparent cured product thereof TOKUYAMA CORP (JP) 2002-09-25 EP disclosed
US-5880170-A TRANSPARENT LENSES FORMED BY CURING TOKUYAMA CORPORATION (JP) 1999-03-09 US disclosed
EP-0795765-A2 Photopolymerizable composition and transparent cured product thereof TOKUYAMA CORPORATION (JP) 1997-09-17 EP disclosed