Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 2/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702396 | 1.00 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2PLK1BRAF | |
| SCHEMBL2997667 | 0.81 | KDM4E (0.55) | TAS1R3TAS1R1TAS1R2BRAFPREP | |
| SCHEMBL13702293 | 0.81 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2BRAFPREP | |
| SCHEMBL13702150 | 0.81 | FDPS (0.57) | TAS1R3TAS1R1TAS1R2BRAFPREP | |
| SCHEMBL13701752 | 0.81 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2BRAFPREP | |
| SCHEMBL8566224 | 0.79 | PLK1 (0.50) | PLK1HDAC8HDAC6THRBHDAC2 | |
| SCHEMBL26415629 | 0.79 | PLK1 (0.50) | PLK1HDAC8HDAC6THRBHDAC2 | |
| SCHEMBL16572977 | 0.79 | CYP1A2 (0.56) | PLK1HDAC8HDAC6HDAC2DDB1 | |
| SCHEMBL29967026 | 0.79 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2BRAFPREP | |
| SCHEMBL1437180 | 0.79 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2BRAFPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676927-A1 | HETEROCYCLIC COMPOUNDS AS WRN INHIBITORS | Synnovation Therapeutics, Inc. (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024187049-A1 | HETEROCYCLIC COMPOUNDS AS WRN INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-09-12 | — | — | WO | disclosed |