Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989680 | 0.86 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2BRAFNPC1 | |
| SCHEMBL9382063 | 0.81 | LMNA (0.47) | POLBMAPTANO1RIPK1NPC1 | |
| SCHEMBL13702396 | 0.81 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2BRAFRIPK1 | |
| SCHEMBL31082091 | 0.81 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2BRAFRIPK1 | |
| SCHEMBL20812677 | 0.81 | LMNA (0.50) | NPC1RAB9ALMNASMN1; SMN2HTT | |
| SCHEMBL13701663 | 0.80 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2POLBMAPT | |
| SCHEMBL15962773 | 0.79 | TAS1R3 (0.57) | TAS1R3TAS1R1TAS1R2ANO1BRAF | |
| SCHEMBL20812506 | 0.78 | KCNK3 (0.54) | POLBMAPTRIPK1NPC1RAB9A | |
| SCHEMBL13701746 | 0.78 | WNT1 (0.44) | POLBMAPTRIPK1NPC1RAB9A | |
| SCHEMBL2997667 | 0.77 | KDM4E (0.55) | TAS1R3TAS1R1TAS1R2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | TAS1R3 3911/4885TAS1R1 4304/4885TAS1R2 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.