Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967026 | 1.00 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2PFKFB3MEN1 | |
| SCHEMBL29957382 | 0.81 | KDM4C (0.61) | TAS1R3TAS1R1TAS1R2KDM4CMAPT | |
| SCHEMBL118817 | 0.81 | KDM4C (0.61) | TAS1R3TAS1R1TAS1R2KDM4CMAPT | |
| SCHEMBL15922749 | 0.79 | TAS1R3 (0.41) | TAS1R3TAS1R1TAS1R2PFKFB3MEN1 | |
| Hydrochloric Acid SCHEMBL28045024 | 0.79 | KDM4C (0.59) | TAS1R3TAS1R1TAS1R2KDM4CMAPT | |
| SCHEMBL3569008 | 0.79 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2PFKFB3BRAF | |
| SCHEMBL2996754 | 0.79 | PARP1 (0.48) | TAS1R3TAS1R1TAS1R2PFKFB3BRAF | |
| SCHEMBL13702396 | 0.79 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2PFKFB3BRAF | |
| SCHEMBL13875969 | 0.79 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2PFKFB3BRAF | |
| SCHEMBL31082091 | 0.79 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2PFKFB3BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704105-B9 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD (GB) | 2025-03-05 | — | — | EP | disclosed |
| US-20240398783-A1 | Compounds and Pharmaceutical Compositions Comprising Inhibitors of Amyloid Peptide Interactions with Glycosaminoglycans, Methods of Treatment and Use Thereof | GISMO THERAPEUTICS, INC. | 2024-12-05 | — | — | US | disclosed |
| EP-3704105-B1 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD (GB) | 2024-10-16 | — | — | EP | disclosed |
| US-20240327386-A1 | AHR INHIBITOR, USE THEREOF, AND PREPARATION METHOD THEREFOR | CHONGQING PHARSCIN INNOBIO CO., LTD. (CN) | 2024-10-03 | — | — | US | disclosed |
| EP-4398902-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF AMYLOID PEPTIDE INTERACTIONS WITH GLYCOSAMINOGLYCANS, METHODS OF TREATMENT, AND USE THEREOF | Gismo Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-117999075-A | Compounds and pharmaceutical compositions comprising inhibitors of amyloid peptide interaction with glycosaminoglycans, methods of treatment, and uses thereof | 吉斯莫治疗股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-115093400-B | AhR inhibitor, application and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114835687-B | AhR inhibitors | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-111566099-B | Antibacterial compounds | 迪斯库瓦有限公司 | 2023-06-02 | — | — | CN | disclosed |
| WO-2023040830-A1 | AHR INHIBITOR, USE THEREOF, AND PREPARATION METHOD THEREFOR | 北京华森英诺生物科技有限公司 | 2023-03-23 | — | — | WO | disclosed |
| WO-2010025451-A2 | 5,8-DIFLUORO-4-(2-(4-(HETEROARYLOXY)-PHENYL)ETHYLAMINO)QUINAZOLINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010025451-A2 | 5,8-DIFLUORO-4-(2-(4-(HETEROARYLOXY)-PHENYL)ETHYLAMINO)QUINAZOLINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2009114552-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2009-09-17 | — | — | WO | disclosed |
| EP-1725101-A1 | 2-PYRIDINYL [7-(SUBSTITUTED-PYRIDIN-4-YL) PYRAZOLO[1,5-A] PYRIMIDIN-3-YL] METHANONES | DOV Pharmaceutical Inc. (US) | 2006-11-29 | — | — | EP | disclosed |
| US-20050277639-A1 | 2-Pyridinyl[7-(substituted-pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones | DOV PHARMACEUTICAL, INC. | 2005-12-15 | — | — | US | disclosed |
| WO-2005084439-A1 | 2-PYRIDINYL[7-(SUBSTITUTED-PYRIDIN-4-YL) PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]METHANONES | DOV PHARMACEUTICAL, INC. (US) | 2005-09-15 | — | — | WO | disclosed |
| WO-2005084439-A1 | 2-PYRIDINYL[7-(SUBSTITUTED-PYRIDIN-4-YL) PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]METHANONES | DOV PHARMACEUTICAL, INC. (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
| WO-1989000560-A1 | DIRECT FLUORINATION OF SUBSTITUTED PYRIDINES | ALLIED SIGNAL INC (US) | 1989-01-26 | — | — | WO | disclosed |
| US-4786733-A | CONTACTING WITH FLUORINE GAS | ALLIED-SIGNAL INC. (US) | 1988-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | TAS1R3 4059/4885TAS1R1 4033/4885TAS1R2 4304/4885 |
| US-20240398783-A1 | Compounds and Pharmaceutical Compositions Comprising Inhibitors of Amyloid Peptide Interactions with Glycosaminoglycans, Methods of Treatment and Use Thereof | PRNP, GBA1, GBA3 | TAS1R3 3028/4885TAS1R1 3796/4885TAS1R2 3538/4885 |
| US-20050277639-A1 | 2-Pyridinyl[7-(substituted-pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones | HTR1A, HTR2B, HTR4 | TAS1R3 1457/4885TAS1R1 1216/4885TAS1R2 1042/4885 |
| US-20240327386-A1 | AHR INHIBITOR, USE THEREOF, AND PREPARATION METHOD THEREFOR | AHR, ARNT, AIPL1 | TAS1R3 4234/4885TAS1R1 4010/4885TAS1R2 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.