SCHEMBL2000882

SCHEMBL2000882

OCc1cc(C(F)(F)F)ccc1C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.50
SRD5A2 P31213 1/20 0.46
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
KLF10 Q13118 1/20 0.41
POLQ O75417 3/20 0.41
IDO1 P14902 2/20 0.41
KIF11 P52732 1/20 0.41
AR P10275 1/20 0.39
MPO P05164 1/20 0.38
CYP26A1 O43174 1/20 0.36
PIEZO1 Q92508 1/20 0.36
DAO P14920 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10183562 0.86 KLF10 (0.46) CES2SRD5A2CYP3A4CYP2D6KLF10
SCHEMBL1993639 0.85 CES2 (0.52) CES2CYP3A4CYP2D6POLQIDO1
SCHEMBL22717044 0.84 CES2 (0.47) CES2SRD5A2CYP3A4CYP2D6POLQ
SCHEMBL1014987 0.83 KLF10 (0.44) CES2CYP3A4CYP2D6KLF10IDO1
SCHEMBL31085526 0.83 KLF10 (0.44) CES2CYP3A4CYP2D6KLF10IDO1
SCHEMBL5252357 0.83 CES2 (0.48) CES2SRD5A2CYP3A4CYP2D6POLQ
SCHEMBL8883258 0.81 CES2 (0.47) CES2SRD5A2CYP3A4CYP2D6POLQ
SCHEMBL102128 0.80 CES2 (0.43) CES2CYP3A4CYP2D6KLF10POLQ
SCHEMBL18002039 0.80 CES2 (0.43) CES2SRD5A2CYP3A4CYP2D6POLQ
SCHEMBL1167122 0.79 IDO1 (0.58) CYP3A4CYP2D6KLF10IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
EP-4570313-A2 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2025-06-18 EP disclosed
EP-4484407-A2 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2025-01-01 EP disclosed
CN-116082563-B (Meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2024-09-20 CN disclosed
CN-118359760-A Optical resin, optical element, and optical device 株式会社 尼康 2024-07-19 CN disclosed
EP-4219477-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2023-08-02 EP disclosed
CN-116082563-A (meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2023-05-09 CN disclosed
US-11142636-B2 (Meth)acrylate compound, additive for optical resin, optical element, and optical device NIKON CORPORATION (JP) 2021-10-12 US disclosed
US-10626095-B2 Cyanotriazole compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2020-04-21 US disclosed
US-20190322857-A1 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2019-10-24 US disclosed
US-20160229816-A1 CYANOTRIAZOLE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2016-08-11 US disclosed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
US-20070276011-A1 Plasminogen Activator Inhibitor-1 Inhibitor INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) 2007-11-29 US disclosed
EP-1666469-A1 PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR Institute of Medicinal Molecular Design, Inc. (JP) 2006-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626095-B2 Cyanotriazole compounds CS, PC, ACAT1 CES2 314/4885SRD5A2 937/4885CYP3A4 1816/4885
US-20070276011-A1 Plasminogen Activator Inhibitor-1 Inhibitor SERPINE1, SERPINC1, SERPINB1 CES2 4194/4885SRD5A2 2223/4885CYP3A4 3320/4885
US-20160229816-A1 CYANOTRIAZOLE COMPOUNDS CS, PC, ACAT1 CES2 314/4885SRD5A2 937/4885CYP3A4 1816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.