Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3111603 | 0.89 | OPRD1 (0.56) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL3119135 | 0.89 | CHRM3 (0.50) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL3119758 | 0.88 | MEN1 (0.52) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL3114898 | 0.88 | MEN1 (0.52) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL3124239 | 0.85 | ALDH1A1 (0.50) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL28095554 | 0.82 | MEN1 (0.59) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL3113370 | 0.81 | OPRD1 (0.50) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL3112449 | 0.80 | SLC6A3 (0.49) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL3122535 | 0.79 | OPRD1 (0.58) | OPRM1OPRD1OPRK1SIGMAR1CHRM3 | |
| SCHEMBL926462 | 0.79 | OPRM1 (0.61) | OPRM1OPRL1OPRD1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179118-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-15 | — | — | US | disclosed |
| EP-2060563-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179118-A1 | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | HRH2, HRH1, HRH4 | OPRM1 158/4885OPRL1 74/4885OPRD1 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.