Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 6/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31094223 | 0.85 | CCNE1 (0.48) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL31094225 | 0.78 | CCNE1 (0.49) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL31094221 | 0.78 | LMNA (0.49) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL23867651 | 0.76 | LMNA (0.53) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL23867576 | 0.76 | LMNA (0.52) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL23867649 | 0.74 | ALDH1A1 (0.52) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL30234817 | 0.74 | LMNA (0.52) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL23867526 | 0.74 | CCNE1 (0.48) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL31094226 | 0.74 | MAPT (0.44) | CCNE1CDK2MAPTLMNAHSD17B10 | |
| SCHEMBL30234364 | 0.74 | CCNE1 (0.48) | CCNE1CDK2MAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024211314-A2 | INHIBITORS OF CHD1L AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2024-10-10 | — | — | WO | claimed |
| WO-2024211314-A2 | INHIBITORS OF CHD1L AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2024-10-10 | — | — | WO | disclosed |