Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358858 | 1.00 | CXCR4 (1.00) | CXCR4KDM4ENR3C2L3MBTL1NAMPT | |
| SCHEMBL5083050 | 0.80 | L3MBTL1 (0.69) | CXCR4L3MBTL1KMT2ASMN1; SMN2ROCK2 | |
| SCHEMBL19358920 | 0.80 | CXCR4 (0.66) | CXCR4KDM4ENR3C2L3MBTL1NAMPT | |
| SCHEMBL5083302 | 0.76 | CXCR4 (0.60) | CXCR4L3MBTL1KMT2AROCK2 | |
| SCHEMBL5079750 | 0.74 | CXCR4 (0.58) | CXCR4L3MBTL1NAMPTSMN1; SMN2ROCK2 | |
| SCHEMBL17101795 | 0.73 | CXCR4 (0.58) | CXCR4NR3C2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5213879 | 0.72 | L3MBTL1 (0.69) | CXCR4L3MBTL1KMT2ASMN1; SMN2ROCK2 | |
| SCHEMBL5079678 | 0.71 | HDAC3 (0.58) | CXCR4L3MBTL1 | |
| SCHEMBL5083115 | 0.70 | TSHR (0.71) | CXCR4NAMPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30474440 | 0.70 | RORC (0.54) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429588-B1 | AMIDE-SULFAMIDE DERIVATIVES, COMPOSITIONS, AND USES RELATED TO CXCR4 INHIBITION | UNIV EMORY (US) | 2024-09-18 | — | — | EP | claimed |