Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.65 |
| ▸ | CDK2 | P24941 | 2/20 | 0.65 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965372 | 0.74 | JAK2 (0.52) | NPC1RAB9ASMN1; SMN2TP53MAPK1 | |
| SCHEMBL31098966 | 0.73 | TNF (0.57) | RAB9ASMN1; SMN2TP53KMT2AEGFR | |
| SCHEMBL31098942 | 0.73 | RAB9A (0.42) | FLT3CDK2CCNA1NPC1RAB9A | |
| SCHEMBL3770171 | 0.73 | PLK4 (0.46) | FLT3CDK2CCNA1NPC1RAB9A | |
| SCHEMBL1921849 | 0.73 | ABCG2 (0.53) | CDK2NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL15502918 | 0.72 | CDK2 (0.49) | FLT3CDK2CCNA1NPC1RAB9A | |
| SCHEMBL13552960 | 0.72 | ALDH1A1 (0.52) | FLT3CDK2CCNA1NPC1RAB9A | |
| SCHEMBL3759489 | 0.72 | F12 (0.52) | NPC1RAB9AKDM4EALDH1A1PLK4 | |
| SCHEMBL13554743 | 0.71 | ALDH1A1 (0.52) | FLT3CDK2CCNA1NPC1RAB9A | |
| SCHEMBL21742928 | 0.71 | KMT2A (0.58) | NPC1RAB9ASMN1; SMN2TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390755-B | Heteroaryl method for amine | 中国科学院理化技术研究所 | 2024-08-02 | — | — | CN | claimed |