Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24050352 | 0.81 | GABRP (0.36) | MAPK8MAPK10MAPTGABRPGABRD | |
| SCHEMBL17052897 | 0.78 | NNMT (0.43) | NNMTMEN1PABPC1KMT2AGABRP | |
| SCHEMBL24045284 | 0.78 | L3MBTL1 (0.39) | MAPTMEN1KMT2ACYP2C9BACE1 | |
| SCHEMBL24554040 | 0.77 | EGFR (0.40) | NNMTMAPTMEN1PABPC1KMT2A | |
| SCHEMBL28897534 | 0.76 | CTSD (0.31) | BACE1 | |
| SCHEMBL25882888 | 0.74 | NNMT (0.47) | NNMTMEN1PABPC1KMT2AGABRP | |
| SCHEMBL11996768 | 0.74 | NNMT (0.50) | NNMTMAPTMEN1PABPC1KMT2A | |
| SCHEMBL8118182 | 0.74 | DRD1 (0.39) | NNMTMAPTTDO2ERN1RPS6KA3 | |
| SCHEMBL23181522 | 0.74 | UHRF1 (0.35) | RPS6KA3 | |
| SCHEMBL12192175 | 0.73 | NNMT (0.46) | MAPK8MAPK10NNMTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255412-A1 | SPIRO HETEROCYCLIC COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2024-12-19 | — | — | WO | disclosed |
| CN-118510780-A | Spiro heterocyclic compounds and uses thereof | 广州必贝特医药股份有限公司 | 2024-08-16 | — | — | CN | disclosed |