Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109985 | 0.84 | ELANE (0.47) | LMNAKDM4ESMN1; SMN2ALDH1A1IRAK4 | |
| SCHEMBL4209791 | 0.82 | KDM4E (0.56) | LMNAKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11314323 | 0.82 | LMNA (0.53) | LMNAKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL32687438 | 0.82 | KDM4E (0.56) | LMNAKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL3961140 | 0.82 | KDM4E (0.45) | LMNAKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8608640 | 0.81 | CYP3A4 (0.43) | LMNAKDM4ESMN1; SMN2ALDH1A1IRAK4 | |
| SCHEMBL9751711 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1IRAK4MAPTCYP3A4 | |
| SCHEMBL28191444 | 0.81 | KDM4E (0.58) | LMNAKDM4EALDH1A1KMT2AIRAK4 | |
| SCHEMBL2987534 | 0.79 | CYP3A4 (0.42) | LMNAKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1244839 | 0.79 | LMNA (0.46) | LMNAKDM4ESMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9339484-B2 | Compositions and methods for the treatment of restless leg syndrome and fibromyalgia | CELLIX BIO PRIVATE LIMITED (IN) | 2016-05-17 | — | — | US | disclosed |
| US-20150133408-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESTLESS LEG SYNDROME AND FIBROMYALGIA | CELLIX BIO PRIVATE LIMITED (IN) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133408-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESTLESS LEG SYNDROME AND FIBROMYALGIA | OPRK1, OPRM1, OPRD1 | LMNA 937/4885KDM4E 3987/4885SMN1; SMN2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.