Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | RGS4 | P49798 | 1/20 | 0.42 |
| ▸ | RGS8 | P57771 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | CD74 | P04233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835720 | 0.71 | KMT2A (0.69) | ALDH1A1LMNASMN1; SMN2MAPK1MAPT | |
| SCHEMBL14038766 | 0.71 | KMT2A (0.56) | ALDH1A1LMNASMN1; SMN2MAPK1MAPT | |
| SCHEMBL23660840 | 0.70 | KMT2A (0.51) | ALDH1A1LMNASMN1; SMN2MAPK1MAPT | |
| SCHEMBL1426816 | 0.70 | KMT2A (0.46) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL4480638 | 0.70 | HPGD (0.66) | ALDH1A1LMNASMN1; SMN2MAPK1MAPT | |
| SCHEMBL31560452 | 0.69 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MAPK1MAPT | |
| SCHEMBL3118165 | 0.69 | MAPT (0.50) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL4392970 | 0.69 | LMNA (0.60) | ALDH1A1LMNASMN1; SMN2MAPK1MAPT | |
| SCHEMBL13440548 | 0.69 | HPGD (0.56) | ALDH1A1LMNASMN1; SMN2MAPK1MAPT | |
| Bromide SCHEMBL1457139 | 0.69 | KMT2A (0.45) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | claimed |
| EP-1789014-B1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KGAA (DE) | 2008-02-27 | — | — | EP | claimed |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | HENKEL KGAA (DE) | 2007-12-13 | — | — | US | claimed |
| EP-1789014-A1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-30 | — | — | EP | claimed |
| WO-2006029687-A1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-03-23 | — | — | WO | claimed |
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | disclosed |
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | disclosed |
| EP-1789014-B1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KGAA (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1789014-B1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KGAA (DE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | HENKEL KGAA (DE) | 2007-12-13 | — | — | US | disclosed |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | HENKEL KGAA (DE) | 2007-12-13 | — | — | US | disclosed |
| EP-1789014-A1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006029687-A1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | KRT18, SCNN1B, COL1A1 | ALDH1A1 210/4885LMNA 374/4885SMN1; SMN2 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.